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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2C1
All Species:
23.33
Human Site:
Y594
Identified Species:
42.78
UniProt:
P13056
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13056
NP_001027458.1
603
67315
Y594
L
K
M
E
P
A
D
Y
N
S
Q
I
I
G
H
Chimpanzee
Pan troglodytes
XP_001137621
678
75113
Y669
L
K
M
E
P
A
D
Y
N
S
Q
I
I
G
H
Rhesus Macaque
Macaca mulatta
XP_001107297
554
61731
Y546
K
T
Y
P
D
D
T
Y
R
Y
L
Q
L
N
S
Dog
Lupus familis
XP_854792
605
67422
Y596
L
K
M
E
P
A
D
Y
N
S
Q
I
I
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q505F1
590
65487
Y581
L
K
M
E
P
A
D
Y
N
S
Q
I
I
G
H
Rat
Rattus norvegicus
Q8VIJ4
590
65509
Y581
L
K
M
E
P
A
D
Y
N
S
Q
I
I
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510105
561
61971
N553
R
M
E
T
A
D
Y
N
S
Q
I
I
G
H
G
Chicken
Gallus gallus
O42101
501
57084
I493
V
P
C
N
N
L
L
I
E
M
L
H
A
K
R
Frog
Xenopus laevis
Q66J63
637
70793
Y628
L
R
M
E
T
S
D
Y
N
S
Q
I
I
G
L
Zebra Danio
Brachydanio rerio
Q06725
411
45463
F403
M
L
L
S
G
S
S
F
N
W
P
Y
M
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16375
543
57969
F535
M
L
L
S
G
N
S
F
S
W
P
Y
L
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4B8
615
68010
F587
L
Q
M
N
L
M
S
F
F
D
Q
K
M
E
L
Sea Urchin
Strong. purpuratus
Q26622
583
63834
S575
N
S
A
Q
I
T
M
S
A
S
P
G
S
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
90.3
96
N.A.
87.5
87.5
N.A.
77.7
21.5
72.6
27
N.A.
22
N.A.
22.9
49
Protein Similarity:
100
87.6
91.2
97.6
N.A.
92.2
91.7
N.A.
84.7
40.9
82.7
42.7
N.A.
37.8
N.A.
42.1
65.1
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
0
73.3
6.6
N.A.
0
N.A.
20
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
13.3
6.6
86.6
40
N.A.
33.3
N.A.
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
39
0
0
8
0
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
16
47
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
8
47
0
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
24
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
0
0
0
0
0
0
8
8
47
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
39
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
8
54
47
0
16
% I
% Lys:
8
39
0
0
0
0
0
0
0
0
0
8
0
8
0
% K
% Leu:
54
16
16
0
8
8
8
0
0
0
16
0
16
8
16
% L
% Met:
16
8
54
0
0
8
8
0
0
8
0
0
16
0
0
% M
% Asn:
8
0
0
16
8
8
0
8
54
0
0
0
0
8
0
% N
% Pro:
0
8
0
8
39
0
0
0
0
0
24
0
0
8
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
54
8
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
8
0
16
0
16
24
8
16
54
0
0
8
8
16
% S
% Thr:
0
8
0
8
8
8
8
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
54
0
8
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _